Weight Loss

Doctor-Led Medical Weight Management at SW1 Clinic

At SW1 Clinic, we recognize that sustainable weight loss is not simply a matter of willpower—it is a medically complex issue influenced by genetics, hormones, metabolic rate, and lifestyle factors. Our evidence-based, physician-led program is designed to support safe, long-term weight reduction with personalized care plans that include clinically validated pharmacotherapy.

Medically Approved Weight Loss Medications

We prescribe only treatments supported by robust clinical data, all of which are approved by the HSA (Singapore), FDA (USA), and EMA (Europe). Each medication is tailored to your health profile and goals, and closely monitored by our medical team.

Phentermine 

• Type: Oral capsule.
• Dose: Once daily, typically in the morning.
• Mechanism: Sympathomimetic that suppresses appetite and boosts metabolism.
• Evidence: Hendricks et al. (Obesity, 2009) reported up to 10% weight loss in 12 weeks when used with lifestyle modifications.
• Best suited for: Short-term use in patients without cardiovascular risks.

Liraglutide 

• Type: Injectable pen (subcutaneous injection).
• Dose: Once daily, titrated gradually to target dose.
• Mechanism: GLP-1 receptor agonist that enhances satiety and slows gastric emptying.
• Evidence: The SCALE trial (Pi-Sunyer et al., NEJM, 2015) showed 8% weight loss at 56 weeks vs. 2.6% with placebo.
• Additional benefits: Improved blood sugar control, reduced risk of progression to diabetes.

Semaglutide 

• Type: Injectable pen (subcutaneous injection).
• Dose: Once weekly.
• Mechanism: Long-acting GLP-1 analogue that reduces appetite and food intake.
• Evidence: STEP 1 trial (Wilding et al., NEJM, 2021) showed 14.9% mean weight loss over 68 weeks.
• Notable for: One of the most effective injectable weight loss medications currently available.

Semaglutide 

• Type: Oral tablet.
• Dose: Once daily, taken on an empty stomach with plain water only.
• Mechanism: Oral GLP-1 receptor agonist, similar in action to injectable semaglutide.
• Evidence: Rosenstock et al. (Lancet Diabetes Endocrinol, 2019) demonstrated significant weight loss and cardiometabolic improvements.
• Ideal for: Patients preferring non-injectable alternatives.

Who Should Consider Medical Weight Loss Therapy?

• Patients with BMI ≥27 and comorbidities such as insulin resistance, prediabetes, dyslipidemia, or PCOS.
• Individuals with BMI ≥30 who have struggled with lifestyle-only weight loss.
• Women experiencing hormonal weight gain (perimenopause or menopause).
• Anyone seeking a safe, clinically supervised alternative to unsustainable dieting or off-label treatments.

Frequently Asked Questions

Are these medications safe?

Yes. All medications are approved by health authorities and backed by large-scale trials. Our doctors assess each patient’s medical profile to ensure safety and suitability.

What side effects should I expect?

Mild nausea, bloating, or early satiety are common and usually subside. Side effects and management strategies will be fully explained during your visit.

How long will I need to take the medication?

Treatment duration is individualized. Some patients may benefit from short-term use; others may require maintenance therapy to prevent rebound weight gain.

Will I regain weight after stopping?

Without sustained behavioral and dietary changes, weight regain is possible. That’s why our program includes ongoing nutrition, coaching, and regular medical reviews.

Medical Weight Loss Treatments – Comparison Table

Start Your Medically-Supervised Weight Loss Journey

At SW1 Clinic, weight loss is never one-size-fits-all. Our program combines the latest in metabolic science with expert clinical care to help you lose weight safely, improve your health, and keep it off for good.

To schedule your consultation, contact SW1 Clinic today.

All medications require a medical consultation. Results may vary between individuals.